Sunday, 21 February 2021

Which of the following is characteristic of B but not T cells ?

1. Which of the following is characteristic of B but not T cells ?




... Answer is D) Surface immunoglobulin

One defining characteristic of B-cells is the presence of membrane immunoglobulin, which T-cells lack. These immunoglobulins are IgMs (μ2L2 "IgG-like" subunits) and IgD, they are anchored in the cell membrane through a specialized C-terminal domain of the heavy chain, and they function as the cells' antigen-specific receptors. Memory B-cells bear membrane-bound isotypes other than IgM, representing whatever Ig the cell will begin secreting upon antigenic stimulation.


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