Monday 22 February 2021

The Class I MHC processing pathway primarily :

1. The Class I MHC processing pathway primarily :

... Answer is A)

MHC class I molecules are one of two primary classes of Major Histocompatibility Complex molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of non-self proteins from within the cell to cytotoxic T cells; this will trigger an immediate response from the immune system against a particular non-self antigen displayed with the help of an MHC 1 class I protein. Because MHC class I molecules present peptides derived from cytosolic- proteins, the pathway of MHC class I presentation is often called cytosolic or endogenous pathway.


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